Publications

Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks

Re: Simulation analysis for tumor radiotherapy based on three-component mathematical models.

Long-term cryopreservation and revival of tissue engineered skeletal muscle.

Quantifying intraleukemic heterogeneity through single cell RNA sequencing.

Quantifying intraleukemic heterogeneity through single cell RNA sequencing.

Optimizing Activation and Purification for Cathepsin Proteases from Engineered Cells

Microenvironment-dependent Models of the Proteolytic Network and Inhibition of Protease Activity

Leveraging single cell RNA sequencing experiments to model intra-tumor heterogeneity

Diversity Dynamics in the Lymphoma Microenvironment Game

The Lymphoma Microenvironment Game – Who Wins Out?

Computational predictions of cysteine cathepsin-mediated fibrinogen proteolysis

Investigating the Life Expectancy and Proteolytic Degradation of Engineered Skeletal Muscle Biological Machines

PACMANS: A Bioinformatically Informed Algorithm to Predict, Design, and Disrupt Protease-on-Protease Hydrolysis

Long-term Expression of Cathepsin K Induces Unexpected Proteolytic Feedback to Maintain Proteostasis

Forward Engineering the Functionality of 3D Printed Skeletal Muscle-Powered Biological Machines

Protease Site-Directed Mutagenesis Distinguishes Cannibalistic Interactions in Proteolytic Networks

Optimizing the Performance and Lifetime of Muscle-Powered Biological Machines

Mathematical Model Reveals Increased Protease Following Inhibition Due to Cannibalistic Regulation

Elucidating the Cathepsin Proteolytic Networks with Informed Mutagenesis and Purified Strategies

Cathepsin Cannibalism Reduces Collagen And Elastin Degradation In Matrix Remodeling